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The median age in these cohorts is about 55 years in the D and DG groups

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Indeed, vaccine effectiveness against VoCs such as Omicron remains high in terms of preventing severe disease and hospitalization despite low serum titres of neutralizing antibodies 109,110,111

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doi: 10.1007/s13671-018-0234-9

Solutions include using a sharper needle (switching from reused to fresh needle for each injection), ensuring the full recommended rotation pattern, and slowing your injection speed