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2 Early symptoms may include gastrointestinal disturbances such as nausea, vomiting, and abdominal pain, which may progress to more severe manifestations, including jaundice, hepatic encephalopathy, and coagulopathy in patients with advanced liver injury
Cytotoxic Drug Resistance Mechanisms
doi: 10.1128/iai.57.9.2776-2781.1989
Demographic data are shown in Table 5
The pH optimum for the active saturable transport is 5.56.0, which explains why antacids seem to reduce folate absorption
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