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Advanced glycation end products (AGEs) and their soluble receptors (sRAGE) as early predictors of reno-vascular complications in patients with uncontrolled type 2 diabetes mellitus

Furthermore, signal transducer and activator of transcription 3 (STAT3) can inhibit the mTOR/HIF-1 pathway by activating AMP-activated protein kinase (AMPK), leading to reduced cell proliferation and increased apoptosis (38)

This has led to significant interest in studies focused on calorie intake, nutrient consumption, weight gain protocols, and bulking-related research

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Cameron et al

Clinical Oncology 24(18S), 2006