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Fatigue and serum testosterone in obstructive sleep apnea patients

Dihexa is not approved by the FDA, EMA, or any other regulatory authority for any indication, and is not in active regulatory development as a drug candidate
NADPH depletion also induces a high cystine/cysteine ratio, leading to disulfide stress, which facilitates disulfidptosis (Dixon et al., 2012)

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1a), is indicative of a nonmutational resistance mechanism