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Kanwar MK, Bhardwaj R (2015) Arsenic induced modulation of antioxidative defense system and brassinosteroids in Brassica juncea L

In earlier clinical trials, IGV-001 demonstrated good tolerance and safety (NCT02507583)

Despite the considerable role of AsA in plant stress tolerance, the role of naturally occurring or synthetic analogs of AsA has rarely been focused

Most current therapies can largely kill cancer progenitors and blasts to induce disease remission, however, due to the failure in elimination of CSCs, cancer relapse is inevitable in most patients (Shibata and Hoque, 2019

Other flavonoids activate Nrf2 pathway includes procyanidin,147 apigenin,148 and chrysin.149 Overall, the effects of flavonoids on the Nrf2/ARE pathway appear to be cell typespecific, concentration dependent, and stage dependent and may vary depending on cancer properties