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Increasingly, it feels like oxidative biology may become the next major scientific frontier in aesthetics
On the other hand, cancer cells sometimes exploit a reversible inactivation of GAPDH via oxidative modification of its active-site cysteine (a GAPDH redox switch), which diverts glucose flux into the pentose phosphate pathway to generate NADPH for antioxidant defense 114

Miao A, Luo T, Hsieh B, Edge CJ, Gridley M, Wong RTC, et al
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Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer

(PubMed) Caldwell KL, Makhmudov A, Ely E, Jones RL, Wang RY
