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PFK-158, the first specific 6-phosphofructo-2-kinase (PFKFB3) inhibitor, has shown broad antitumor activity in a variety of human and preclinical models, and the clinical value of PFK-158 in patients with advanced pancreatic cancer has been reported in a related multicenter clinical trial (NCT02044861) [92]

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36687-82-8 Usage Uses Used in Pharmaceutical Applications: L-Carnitine-L-tartrate is used as a dietary supplement in the pharmaceutical industry

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations