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Importantly, this study also demonstrated that the B12 reduction associated with metformin use is not transitory but persists and progresses over time and, in some patients, to levels at which replacement is recommended

Is blood withdrawal for medical or anti-doping tests allowed

M.ViolletB.et al (2011)

(DOCX) S1 Data

Figure 13

That is why I was worried, since you seem to say dosing for a long time could lead to cancer
