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Description
Capmatinib is an ATP-competitive and highly selective small molecule c-MET receptor TKI that demonstrated inhibition of MET activation in cancer cells whose growth is driven by MET amplification, MET overexpression, MET exon 14 skipping mutations, and HGF-mediated activation (Baltschukat et al., 2019)

J Inorg Biochem 195:111

[DOI] [PubMed] [Google Scholar] 33.Yabe D., Seino Y

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Moreover, knockout (KO) mice lacking the antioxidant transcription factor Nrf2 displayed depression-like behaviors in various tests (Dang et al., 2022
