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10.3389/fcell.2021.696542 264 ZhangY.WenP.LuoJ.DingH.CaoH.HeW.et al (2021b)

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Additionally, mitochondrial disorders such as MELAS syndrome can cause non-vascular acute neurological dysfunction, leading to stroke-like episodes [163]

These symptoms markedly reduce quality of life and are associated with stress-induced psychological sequelae that contribute to anxiety, depression, low self-esteem, and relationship strain

Osteoporosis Osteoporosis is an age-related bone disease characterized by reduced bone mass and alterations in bone microstructure, leading to increased fragility and a greater risk of fractures, particularly among elderly individuals