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The thinking: if you can isolate just the fat-related fragment, you get that one effect on its own
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When NNMT is inhibited: NAD+ levels rise Mitochondria become more efficient Cells burn more energy, even at rest This effect helps the body shift into a more metabolically active state, making it easier to reduce fat and preserve muscle during weight loss

Scand J Haematol 1964;1:5-15

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