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Despite being discovered first, it received less clinical attention for decades because early research suggested that GIP signaling was impaired in type 2 diabetes, making it seem like an unlikely therapeutic target

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Retatrutide is significantly more effective than tirzepatide (Mounjaro)

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A standard 3 mL peptide vial comfortably holds up to about 3 mL, and many so-called "10 mL" vials are only partially filled by design to leave headspace

Its role in immunoregulation is under investigation, including potential antiviral effects
