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[DOI] [PubMed] [Google Scholar] 116.Reguera M.J., Ferrer L., Rabanal R.M

10.2174/13816128130111 [DOI] [PubMed] [Google Scholar] Sikiric P., Separovic J., Anic T., Buljat G., Mikus D., Seiwerth S., et al

We also allow the inputs to vary as functions of time (for example the amino acid input will vary because of meals) and compute the time course of each concentration and reaction rate

The evolution of GSH in aging fibroblasts showed a sudden increase in its concentration just before cell death, whereas GPx activity was already decreasing at the beginning of passages, and that of glutathione reductase was constant and reaching a very low level at the end of the cell culture, suggesting that the GSH system was probably involved in cell degeneration associated with aging [18]

CSCs have been linked to chemoresistance in cancer patients, which accounts for 90% of treatment failures
