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Understanding the safety profiles and regulatory status of research peptides remains essential for responsible laboratory use and experimental design

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We discuss how T1D is fundamentally a disease caused by failures in central and peripheral tolerance mechanisms, leading to the activation and infiltration of autoreactive CD4+ and CD8+ T cells into the pancreatic islets

doi: 10.3389/fmicb.2025.1526250 Received 11 November 2024 Accepted 13 January 2025 Published 03 February 2025 Volume 16 - 2025 Edited by Sebastian Guenther, University of Greifswald, Germany Reviewed by Eugene A

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