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Global Epigenomic Reconfiguration During Mammalian Brain Development

MILD is a minimally invasive, image-guided procedure performed through a small port (about the size of a pencil) under live X-ray guidance

doi: 10.1177/0300060518789299 98 LarssonA

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The MnSOD gene polymorphism (Val16Ala, also referred to as Val9Ala in some studies) results in an Ala variant at position 9 in the mature protein (position 16 in the precursor protein) that increases the efficiency at which MnSOD is transported into the mitochondria, theoretically promoting hydrogen peroxide generation in this organelle (381)