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Notably, mitochondrial ROS levels were found to be elevated in both mice and rats subjected to CS exposure
Pharmacogenomics Pharmacoproteomics 5:5

Furthermore, many of the features of Parkinson's disease have a mainly non-dopaminergic basis

Clin Rev Allergy Immunol 2009;36(1):4-12

Blocking complex I with rotenone causes Parkinson-like dysfunction in animal models

Furthermore, astrocytes regulate synaptic function by modulating synaptic transmission and plasticity, buffering extracellular K + , taking up neurotransmitters, and releasing gliotransmitters