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The enzyme GR then reduces the oxidized form of glutathione, glutathione disulfide (GSSG), to GSH with NADPH as the reductant (Foyer and Halliwell, 1976)

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Introduction Despite considerable technological developments and continuous research to find and implement an effective and safe drug, there are still none that have positive therapeutic effects, target multiple disease entities, and, at the same time, have no side effects