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Discussion The term plateau refers to an area at least 3000 m above sea level, and its typical climatological characteristics are cold temperatures, low partial pressure of oxygen and high solar radiation

However, these studies are small and need much more follow up work before any conclusions are drawn from it [50]

Peer review Peer review information Nature Reviews Drug Discovery thanks the anonymous reviewers for their contribution to the peer review of this work

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Freo et al., 2009

Diet and Exercise Recommendations A balanced diet and controlled exercise can support heart health and delay the progression of dilated cardiomyopathy in dogs: Heart-Healthy Nutrition : Feed your dog a complete and balanced diet that meets AAFCO standards to ensure all essential nutrients are provided