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The American Academy of Neurology (AAN) has a well-published guideline for treatment that includes gabapentinoids, anticonvulsants and antidepressants.6 Despite the availability of multiple pharmacologic therapies, many patients continue to have uncontrolled pain or cannot tolerate side effects

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They may develop a loss of energy and appetite and failure to thrive, which if not treated on time can lead to coma and death

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This is why aliquoting, the practice of dividing your reconstituted solution into smaller single-use or few-use vials before freezing, is so important