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The bottleneck logic is worth restating because it explains when stacking helps at all: adding a second compound only matters if it clears a different rate-limiting step than the ones already covered

H 2 S also acts as an endogenous inhibitor of phosphodiesterase activity (57)

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Testing should include TSH, free T4, free T3, and thyroid antibodies at minimum, interpreted using functional optimization ranges rather than just laboratory reference ranges

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