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Tissue-Specific Distribution: The selectivity is further enhanced by the tissue distribution of beta-3 adrenergic receptors

In mammals, these hormones peak during puberty and decline gradually during adulthood and aging

If you need to just take 25mcg of t3 to return to baseline and the L-CARITINE is assisting in fat loose through a way that doesn't increase blood pressure or heart rate...it's worth it IMHO Well if the issue that Scott stated is that it doesnt allow t3 to enter the cell properly, I would assume that could possibly still translate to exogenous t3 no

References Fu QR, Wei C, Wang MZ

[DOI] [PubMed] [Google Scholar] [170].Meex RC, Schrauwen-Hinderling VB, Moonen-Kornips E, Schaart G, Mensink M, Phielix E, van de Weijer T, Sels JP, Schrauwen P, Hesselink MK

10.1016/j.bbrc.2011.05.155 47 FarkasG.KirlyZ.SolymosiF