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Co-immunoprecipitation mass spectrometry and CRISPR KO in cells identified that mitochondrial m -AAA protease AFG3L2 is responsible for degrading SLC25A39 through the matrix loop 1

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Liposomes are a suitable drug delivery system that could be used for drug delivery in the brain by crossing the BloodBrain Barrier

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The method involves a simple and efficient two-step preparation procedure consisting of liquidliquid extraction of the urinary acids followed by a microwave-assisted esterification of the isolated compounds using 2-propanol