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Regulation of glucose and glutamine metabolism to overcome cisplatin resistance in intrahepatic cholangiocarcinoma

These antioxidant deficits facilitate oxidative damage to neuronal membranes, impair mitochondrial function, and disrupt neurotransmission, further exacerbating depressive symptoms [95]

Oxidative stress is the damage caused by unstable molecules called free radicals, which we encounter through diet, pollution, and natural metabolic processes

Another characteristic of PD is oxidative DNA damage, which triggers PARP activation, leading to the depletion of NAD + levels 40,279,282,283,284
Access this article Similar content being viewed by others REFERENCES Dieck, C.L., Tzoneva, G., Forouhar, F., Carpenter, Z., Ambesi-Impiombato, A., Snchez-Martn, M., Kirschner-Schwabe, R., Lew, S., Seetharaman, J., and Tong, L., Cancer Cell , 2018, vol

Older patients should be administered Neurobion Forte RF Injection under medical supervision as they may be more susceptible to its side effects
