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The two are not interchangeable, and you should not convert one into the other

In the healing of the perforated stomach in the first 15 min, there was initially elevated NOS-2 and decreased VEGFa, then elevated NOS-2 and decreased VEGFa, then elevated COX-2, NOS-1, NOS-2, NOS-3, and then elevated COX-2, NOS-2, and decreased NOS-3 gene expression [144]

& Grimsby, G

Likewise, as a common point, there was a shared annihilation of the intervening connective tissue layer that separates the muscle from the bone (muscle-to-bone detachment) or muscle from the gap area (transected muscle) [30] and shared purposeful muscle cell proliferation

Ask it "what is the technical objective," "summarize the eligibility section," "what is the agency really asking for," "who is the likely Phase III customer" and get a structured answer instead of re-reading the topic for the third time