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Such a study requires a drug which is practically specific for one condition whose prevalence is known, and the one which approximates most closely to this appears to be vitamin B12

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Cholinergic cortical and thalamic pathways were reconstructed using probabilistic tractography on diffusion images, followed by the quantification of the disruption in these tracts with diffusion metrics derived from neurite orientation dispersion and density imaging (NODDI) model

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Frequency: Once per day subcutaneously, preferably at bedtime [2]

We discuss the transduction of luminal stimuli further in sect