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The original goal of the staple was to get the peptide into the cell, but it turns out the staple can also enhance the binding and enhance the specificity, Keating says

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(Published) Peer-Reviewed Abstracts (Published/Presented) Campbell, J., Larson, R., Black, C., FACSM, McGuire, K., (2019) Performance Recovery In Army Reserve Officer Training Corps Cadets Following A Bout Of High-Intensity Exercise