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Unchecked oxidation is a destructive process that results in breakdown, illness and cellular death

L.et al (2016)

The peptide also improved mature collagen organization more effectively than PDGF-BB (becaplermin) in diabetic models

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Traditional approaches such as chimerization and CDR grafting have been instrumental in this regard, while current efforts are increasingly focused on fully hAb formats derived from transgenic animal platforms (e.g., HuMab Mouse, VelocImmune) or synthetic libraries