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Using them without medical supervision introduces unnecessary risk

Blundell, J., et al

As evidence for the possibility of an early life disturbance creating lasting effects on barrier function, the trauma of maternal separation during weaning has been shown to predispose adult rats to enhanced intestinal permeability in response to stress [51]
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Higher magnification images suggested a reduction in MBP and MOG expression in the corpus callosum 24 h post CPZ-treatment (Figures 2B,E)

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