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Monoclonal L235 Fab antibody fragment was made by digestion of mouse anti-human MFI2 Ab with papain (Sigma-Aldrich, Oakville, ON), and the resulting Fab fragment was directly conjugated with Cy5

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doi: 10.1016/j.foodchem.2003.09.023

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According to board-certified dermatologist Blair Murphy-Rose, MD, consumers will first notice these pigments in the palms, soles, and other thick layers of skin