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glutathione ibd Bifidobacterium bifidum Ameliorates DSS-Induced Colitis in Mice by Regulating Microbial Metabolome and Targeting Gut Microbiota Increased Expression of Extracellular Glutathione
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indicated that preoperative treatment with melatonin (10 mg/day, P.O for 30 days) notably raised Nrf2 levels in peripheral blood mononuclear cells of patients undergoing coronary artery bypass grafting (CABG) [208]

doi:10.1016/j.juro.2011.12.076 1040. Dahadhah FW, Saleh Jaweesh M, Al Zoubi MS, Issam Abu Alarjah M, Hammadeh ME, Amor H

Shah SA, Khan M, Jo MH et al (2017) Melatonin stimulates the SIRT1/Nrf2 signaling pathway counteracting lipopolysaccharide (LPS)-induced oxidative stress to rescue postnatal rat brain

Ann Braz Acad Cienc 97:114 Durairaj V, Muddasarul H, Garima S, Sankar P, Preedia B, Rukkumani R (2014) Phytochemical screening and analysis of antioxidant properties of aqueous extract of wheatgrass

Although thioredoxin-(TRx-) and GSH-dependent pathways have overlapping functions in plants [117,118], Mhamdi and co-workers (2010) demonstrated no upregulation of TRx-dependent genes in increased H 2 O 2 conditions like cat2 and gr1cat2 , providing evidence that GR1 plays a specific role in intracellular H 2 O 2 metabolism

In mouse models of colitis, GfDEVs help macrophages stay in a regulatory, inflammation-resolving state [38, 184]
