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Stephen Tapanes, PhD 1 Overview Summary and Quick Facts for Atherosclerosis and Cardiovascular Disease Atherosclerosis can occur anywhere in the body, but it is particularly dangerous when it affects the arteries that supply oxygenated blood to essential organs such as the brain and heart

We propose that the underlying mechanism behind that impact may be related to the mitigation of cellular oxidative damage and glycolipotoxicity, according to previous evidence from preclinical and clinical studies

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Mergenthaler P, Balami JS, Neuhaus AA, Mottahedin A, Albers GW, Rothwell PM, et al

Thus, the use of ALA as an adjuvant in DM management is related to its capability to inhibit glycation which generates free radicals [82,86,87]