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The vast majority of autophagy-regulated molecules show autophagy-independent functions, although for some of the proteins known to be involved in autophagy, there have not been annotated non-autophagy roles (e.g., ATG2), most likely because of theoretical or technical limitations [162]

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141 143 Chauhan et al 135 showed that the expression of ETC complexes (1, 2, 3, 4, and 5) is decreased in the cerebellum as well as frontal and temporal regions of the brain in children with autism, leading to abnormal energy metabolism and increased vulnerability to oxidative stress

Accinni R, Rosina M, Bamonti F, Della Noce C, Tonini A, Bernacchi F, Campolo J, Caruso R, Novembrino C, Ghersi L, Lonati S, Grossi S, Ippolito S, Lorenzano E, Ciani A, Gorini M

Tveit KS, Brokstad KA, Berge RK, et al

doi: 10.1038/s41591-019-0695-9 409 ZlokovicB