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Many nerve cells also use NO to signal neighboring cells: NO released by nerve terminals in the penis, for instance, acts as a local mediator to trigger the blood-vessel dilation responsible for penile erection

Experimental studies report activation of signaling mechanisms related to vascular remodeling, including Notch-associated pathways and endothelial cell activation in angiogenesis models [8]

B., Margaretten, K., Ding, X., Guandalini, S., Comstock, L., & Goldblum, S

Letelier et al

ROS production in the cochlea has been documented through both in vivo and in vitro studies
