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An Arabidopsis ( Arabidopsis thaliana ) mutant lacking all three DHARs ( D dhar ), with negligible DHAR activity, was shown to be equivalent to wild-type plants in terms of growth and development, as well as ascorbate levels (Rahantaniaina et al., 2017)

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NNMT depletes cells of NAD+, a crucial coenzyme required for mitochondrial function and energy production

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