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This is also common in people taking medications like Proton Pump Inhibitors (PPIs) or metformin , which can block the absorption of B12 and other B vitamins
Kerver JM, Pearce EN, Ma T, Gentchev M, Elliott MR, Paneth N
VIT B12 supplementation impact on PD: guidelines and recommendations B12 supplementation: Pathogenesis, motor and non-motor outcomes in PD As pointed out in the first sections of this article, Vit B12 does significantly impact PD pathogenesis
Finally, B12 in the form of hydroxocobalamin is often given once every three months
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doi: 10.1016/j.drudis.2022.103464
