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This paper provided early evidence for IGF1R-mediated resistance to other targeted therapies
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10.3389/fphar.2022.936677 148 ShiX.XieX.SunY.HeH.HuangH.LiuY.et al (2020)
Alternatively, a combined therapy comprising rhGH plus recombinant human IGF-I (rhIGF-1) appears to be an effective treatment option in some cases
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