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Its unique overexpression pattern in the TME, coupled with its absence in normal adult tissues, makes EDB a selective target for nanotechnological strategies [164]

Mol Cell Biol 28:133847, PMID: 18086890 Haddad JJ (2002) The involvement of l-gamma-glutamyl-l-cysteinyl-glycine (glutathione/GSH) in the mechanism of redox signaling mediating MAPK(p38)-dependent regulation of pro-inflammatory cytokine production

Lypolysis is the metabolic action of breaking the triglyceride into its smaller parts (three fatty acids + one glycerol) for ATP production

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Generally, subsets like iCAFs, LRRC15 + myCAFs, and senescent CAFs are pro-tumorigenic and immunosuppressive

Biochimie 100, 7887
