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Generating somatic knockout cell lines with CRISPR-Cas9 technology to investigate SMAD signaling

C., Kuca, K., Medina-Franco, J

In addition, this study identified a strong association between two blood metabolites (cysteine-glutathione disulfide and 3-indole-glyoxylic acid) and the risk of NAFLD, offering new avenues for early detection and treatment of NAFLD

Finding that interesting loop later led to our understanding of the sensing mechanism, Birsoy says
