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KD of Lc3 in skin organoids using shRNA significantly reduced cell proliferation and impaired hair regeneration postorganoid transplantation (Fig

Tesamorelin is FDA-approved as Egrifta for visceral fat reduction in HIV lipodystrophy, and Sermorelin held a past FDA approval before being discontinued for business reasons

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Overall, these preclinical studies suggest that sulforaphane may have potential as a neuroprotective agent in the treatment of NDs, and more research studies are still needed in the future to determine its safety and efficacy in humans