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Glutathione-deficient mice have increased sensitivity to transplacental benzo[a]pyrene-induced premature ovarian failure and ovarian tumorigenesis.Cancer Res

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The intuitive reason that GSH(t) is fairly stable is that GSH changes quite slowly when estradiol and S ( t ) vary

Effects of 17beta-estradiol on sympathetic activity and pressor response to phenylephrine in ovariectomized rats