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[DOI] [PubMed] [Google Scholar] Liu Y., Liu J., Yin P., Gao M., Deng C., Zhang X

The desired result of this resting state of the insulin biosynthesis apparatus can be ideally a cessation of proinsulin folding and thus a reduction of H 2 O 2 generation, thereby reducing the ER stress

Those studies identified a new function of xCT antiporter as a regulator of nutrient flexibility by antagonizing glutamine metabolism

While A4V and the artificial copper site mutant H46R/H48Q have a 40-fold and 220-fold reduction in their ability to form a dimer, respectively, G93A and I149T have wild-type-like dimer interactions

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