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Scott et al., 2005

International society guidelines published prior to this date were reviewed from the American Academy of Neurology (AAN), European Academy of Neurology (EAN), and Japanese Society of Neurology, as well as national guidelines from Canada and Iran

However, the mechanism of cell type-specific ferroptosis sensitivity remains unclear, and the inherent susceptibility to ferroptosis of untreated cancers varies significantly by organ system 39

Human data are mostly limited to short-term interventions, and direct measurement of lysosomal activity or autophagic flux in clinical trials remains challenging due to the lack of standardized, non-invasive biomarkers [30]

Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders

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