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KNA is supported by an NSF Graduate Research Fellowship (DGE 1752814 & 2146752) and a UC Berkeley Fellowship

Thymosin Beta-4 (the parent molecule of TB-500) has been shown in various in-vitro models to upregulate the expression of MMPs, such as MMP-2

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12 Glycine and Oxidative Stress Current research also shows that glycine supplementation protects against oxidative damage by increasing levels of glutathione, an antioxidant that reduces the harmful effects of oxidative stress by reducing free radicals

LicoA was dissolved in dimethyl sulfoxide (DMSO) to prepare a 10 mM stock solution and stored at 20 C

Pharmacokinetic and toxicity predictions suggest that the lead compounds have drug-likeness properties