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An immunoblotting analysis of BiP, an ER-localized protein and VDAC1, a mitochondrial membrane protein showed that preparation of microsome fraction was successful, although a portion of BiP was fractionated in mitochondria (Fig

Enhance activity of GPX mimetics For some GPX mimetics, its activity can be enhanced by electrondonating

Excessive neuronal iron promotes NFT formation via the activation of CDK5 (Cyclin-dependent kinase 5)/P25 complexes and GSK-3 (Glycogen synthase kinase-3 beta) kinase pathways

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Glutathione deficiency is a serious problem

Excessive intake of dietary sugars, particularly fructose, further stimulates DNL, driving hepatic fat accumulation and steatosis [61]