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87 The protective effect of quercetin on colon cancer was investigated in 45 rats using azotoxin methane (15 mg/kg s.c.) as a carcinogen

Melatonin expresses anti-inflammatory and antioxidant properties, and regulates different biological functions such as sleep, circadian rhythm, immunity, reproduction and blood pressure control

discussion 817-20, 2005
The response to ER stress plays a pivotal role in MTX-induced apoptosis, where MTX primarily triggers ER stress via the PERK/CHOP pathway (Song et al., 2021)

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This may help prevent undigested proteins from fermenting in the gut microbiome, significantly reducing the bloating, gas, and GI pain often experienced by patients with compromised digestion
