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122 , e70176 (2025)
Aging, antagonistic pleiotropy and fibrotic disease
Glucose, a primary carbon source, is well known for its rapid breakdown and efficient energy supply to fungal organisms (Garraway and Evans 1984), aligning with the findings of numerous studies on basidiomycetes (Krupodorova et al
To further test the role of GCL in modulating glutathione and glutamate, we utilized sulforaphane, which increases GCL expression through activation of the Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) pathway (22)
These results correlated with a reduced percentage of HbA1c, fasting glycaemia, and HOMA index, as well as improvements in other clinical parameters related to cardiovascular function, lipid profile, and body composition [100]
doi: 10.1093/jn/121.7.1054 144 BuckmasterPSHollidayTABaiSCRogersQR
