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For SAH, the endovascular perforation model is widely used because it can simulate SAH caused by rupture of aneurysm ( Degradation products of hemoglobin (ferrous iron and heme) play an essential initiating role in the induction of these pathophysiological events

Cancer cells exhibit remarkable plasticity to rewire their metabolic fluxes by mobilizing alternative biosynthetic precursors or activating salvage pathways [268]

Nevertheless, the observed occipital depletion aligns with broader evidence of redox imbalance and impaired mitochondrial function in depressive disorders

Ferroptosis, when it occurs in neutrophils or airway epithelial cells can thus cause excessive immune activation, leading to autoimmune disease (Figure 3)

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Across diverse CNS disease contexts, these agents have reduced inflammatory readouts and improved functional outcomes in vivo [189,190,191]