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doi: 10.1111/ijfs.13006 78 XiaoJ.NiX.KaiG.ChenX

Reddy NM, Kleeberger SR, Bream JH, Fallon PG, Kensler TW, Yamamoto M, Reddy SP (2008) Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling

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In short, the antioxidant capacity of the urate or the immune changes it causes may influence the inflammatory progression
Similarly, the H 2 S-donor GYY4137 (250 M) significantly reduced the activity of MMPs in mesangial cells exposed to Hcy (50 M for 30 min)