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Gong et al., 2021

Worse still, their accumulation in tissues contributes to chronic inflammation, degenerative diseases and general ageing of the body

Connect with social workers at hospitals and develop referral relationships with healthcare providers serving low-income populations

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Methylglyoxal, a precursor of AGEs, poses a particular threat to neural tissue, and both of these toxic compounds have been found in the brains of people with Alzheimers disease
Mechanistically, MBOAT1/2, which are lyso-PL acyltransferases (LPLATs), change monounsaturated fatty acids (MUFAs) into lyso-phosphatidylethanolamines (lyso-PEs), increasing the levels of PE-MUFAs and decreasing the levels of PE-PUFAs to suppress phospholipid peroxidation and inhibit ferroptosis [91]
