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Transcobalamin receptor-knockout mice with Cbl deficiency exhibit both myelin loss and central nervous system inflammation, as demonstrated in animal studies

doi: 10.3389/fmed.2025.1535673 Received 27 November 2024 Accepted 25 March 2025 Published 04 April 2025 Volume 12 - 2025 Edited by Vasilios Kotsis, Aristotle University of Thessaloniki, Greece Reviewed by Panagiota Anyfanti, Aristotle University of Thessaloniki, Greece Raina D Ramnath, University of Bristol, United Kingdom Updates Copyright 2025 Wang, Zhang, Qu and Zhou
The 53 users' observational dataset produced highly mixed results

Most patients require 3-6 months of consistent therapy for lasting improvements

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When processed and subjected to audio output on an EMG system, these high-frequency discharges can produce sounds ranging from a ping to a high-pitched whine
